Job Description

Position Overview:

Senior Director of Biology (Translational) to join a dynamic and fast-paced biotech company. This individual will lead the design and implementation of disease biology and mechanism of action (MoA) studies, focusing on advancing drug development. The ideal candidate will have deep experience in experimental biology, a strong understanding of biomarker development, and the ability to synthesize complex biological data into actionable insights.

This role will offer you the opportunity to work with a talented team to push innovative drug candidates through the pipeline and bring transformative therapies to the clinic.

Key Responsibilities:

• Lead the design and execution of disease biology studies, defining MoA and biomarkers for therapeutic candidates.
• Synthesize and integrate complex biological data, providing clear and actionable insights to drive drug development decisions.
• Design and drive experimental and translational biology strategies, ensuring rapid turnaround of biology deliverables.
• Mentor and manage a small team of scientists, fostering a collaborative and high-performance environment.
• Collaborate closely with cross-functional teams, including clinical, regulatory, and commercial, to ensure alignment on program goals and timelines.
• Lead the biological component of drug development, from preclinical to clinical phases, ensuring scientific rigor and innovation.
• Stay abreast of scientific advances in disease biology and therapeutic modalities, leveraging new technologies and approaches where applicable.
• Provide leadership in the integration of bioinformatics and experimental biology to enhance data analysis and decision-making.

Qualifications:

• PhD in Biology, Biochemistry, Molecular Biology, or related field.
• 8-10 years of experience in a biotech or pharmaceutical environment, ideally with experience in fast-paced, startup settings.
• Strong expertise in disease biology, mechanism of action (MoA), and biomarker discovery.
• Experience in cardiovascular biology is highly preferred, though candidates with experience in other therapeutic areas will be considered if they have strong MoA characterization experience.
• Experience in experimental biology, translational biology, and rapid data integration.
• Proven leadership experience, including managing a team of scientists and coordinating with cross-functional teams.
• Strong communication skills, with the ability to clearly articulate complex biological findings to non-scientific stakeholders.
• Expertise in bioinformatics and its application in experimental biology is a plus.
• A proactive, hands-on, and team-oriented approach to leadership.

Location:

• Will be required to work in the lab 3 days a week, California

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